Rooker is determined to find out how Darkman has his superior strength, and enlists the aid of Dr Bridget Thorne, the doctor who originally worked on Westlake's body when he was burnt in the first movie.

Gaining a sample of Westlake's adrenaline, Dr Thorne develops a designer steroid which enhances someone's strength at the cost of their mental agility.

Learning of what has happened, Darkman plans his revenge against Rooker by impersonating him to his family and colleagues in order to bring him down.

It is upto Darkman to destroy the formula to the steroid and seek vengeance against Rooker, but not at the cost of Rooker's wife and child. 

Arnold Vosloo continues his dual role as Westlake and Darkman: this time he does have some touching moments with Rooker's wife (played by Roxanne Biggs-Dawson), and his child, reminding him of life could have been for him.

Jeff Fahey as Peter Rooker give an over the top performance as the main villain of this movie, he is joined by Darlanne Fluegel as Dr. Bridget Thorne, a new character retroactively put into Darkman's origin as one of the doctors who first treated him.

The idea of the super steroid developed from Westlake's adrenaline is intriguing, no doubt inspired by news stories of designer drugs at the time.

This was originally intended as the first sequel to the series, but when Larry Drake became available to reprise his role of Durant, this entry was moved back until Darkman II: The Return of Durant had been finished and released.